A novel profluorescent probe for detecting oxidative stress induced by metal and H2O2 in living cells

A profluorescent probe that has no fluorescent response to H2O2, iron or copper ions but can be readily activated in the presence of both H2O2 and Fe (or Cu) ion has been developed; the probe is capable of detecting oxidative stress promoted by Fe (or Cu) and H2O2 (i.e. the Fenton reaction conditions) in living cells.