An efficient entry to furo[2,3-d]pyrimidines via inverse electron demand Diels–Alder reactions of 2-aminofurans with 1,3,5-triazines
2009
Abstract Furo[2,3- d ]pyrimidines were readily prepared via an inverse electron demand Diels–Alder (IDA) reaction between 2-aminofurans and 1,3,5-triazines. 2-Aminofurans proved to be productive dienophiles leading to the IDA product in moderate to good yields. This study further expanded the scope of 1,3,5-triazine IDA reactions with five-membered aromatic heterocycles as dienophiles.
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