To determine the predictive value of preoperative breast MRI in selecting patients appropriate for nipple-sparing mastectomy.

e11579 Background: The presence of the nipple areolar complex (NAC) is fundamental to the identity and esthetic of the breast. The objective of the nipple-sparing mastectomy is to preserve this in the appropriate setting. However, accurate patient selection is critical prior to performing a nipple-sparing mastectomy (NSM). Currently, there is a paucity of evidence to assist surgeons in developing an oncologically safe selection criteria. The aim of this study is to determine the utility of preoperative breast MRI to more accurately select patients for this procedure. Methods: All patients undergoing mastectomy with a preoperative MRI (within 3 months) were reviewed over a two-year period at a single institution. Preoperative breast MRI results were compared with the final pathological mastectomy specimen report. Patients were excluded if they had a lumpectomy prior to MRI. Patients were also excluded if Paget’s disease of the nipple-areolar complex was present and if inflammatory breast cancer was suspect...