Guillain–Barré syndrome risk among individuals infected with Zika virus: a multi-country assessment

Background Countries with ongoing outbreaks of Zika virus have observed a notable rise in reported cases of Guillain–Barre syndrome (GBS), with mounting evidence of a causal link between Zika virus infection and the neurological syndrome. However, the risk of GBS following a Zika virus infection is not well characterized. In this work, we used data from 11 locations with publicly available data to estimate the risk of GBS following an infection with Zika virus, as well as the location-specific incidence of infection and the number of suspect GBS cases reported per infection.