Combined Effects of Gamma Radiation and High Dietary Iron on Peripheral Leukocyte Distribution and Function

, monitored immune parameters in the peripheral blood of rats subjected to gamma radiation, high dietary iron or both. •Specific immune measures consisted of: -peripheral leukocyte distribution -plasma cytokine levels -cytokine production profiles following whole blood mitogenic stimulation •Both radiation and increased iron stores can independently increase oxidative damage, resulting in protein, lipid and DNA oxidation. •Oxidative stress increases the risk of many health problems including cancer, cataracts, and heart disease.