In Vitro Susceptibility of 50 Non-β-Lactamase-Producing Neisseria gonorrhoeae Strains to 12 Antimicrobial Agents

Abstract The in vitro activities of six commonly used antibiotics and six newer β-lactam agents were determined in 50 consecutive clinical isolates of β-lactamase-negative Neisseria gonorrhoeae. The gonococci isolated were notably resistant to penicillin, ampicillin, erythromycin, and tetracycline, whereas all of the strains were susceptible to the newer β-lactam agents cefoxitin and spectinomycin.