Progression Rate From Intermediate to Advanced Age-Related Macular Degeneration Is Correlated With the Number of Risk Alleles at the CFH Locus.

Rebecca J. Sardell,Patrice Persad,Samuel S. Pan,Patrice L. Whitehead,Larry D. Adams,Renee Laux,Jorge A. Fortun,Milam A. Brantley,Jaclyn L. Kovach,Stephen G. Schwartz,Anita Agarwal,Jonathan L. Haines,William K. Scott,Margaret A. Pericak-Vance

Progression Rate From Intermediate to Advanced Age-Related Macular Degeneration Is Correlated With the Number of Risk Alleles at the CFH Locus.

2016

Rebecca J. Sardell
Patrice Persad
Samuel S. Pan
Patrice L. Whitehead
Larry D. Adams
Renee Laux
Jorge A. Fortun
Milam A. Brantley
Jaclyn L. Kovach
Stephen G. Schwartz
Anita Agarwal
Jonathan L. Haines
William K. Scott
Margaret A. Pericak-Vance

Purpose Progression rate of age-related macular degeneration (AMD) varies substantially, yet its association with genetic variation has not been widely examined.

Keywords:

Anatomy
Macular degeneration
Cancer research
Genetic variation
Locus (genetics)
Choroidal neovascularization
Single-nucleotide polymorphism
Genotype
Allele
Biology
Proportional hazards model
Oncology
Internal medicine
SNP
Survival analysis
Hazard ratio

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