Synthesis of Methyl m-Trifluoromethylbenzoate
2011
Methyl m-trifluoromethylbenzoate is synthesized using m-methyl benzoyl chloride as a starting material,comprising 3 steps of side-chain chlorination,fluorination and esterification.The key techniques are resolved such as a special light source of chlorination,the catalyst of fluorination and the deacid regent of esterification.The optimized process conditions are obtained which suitable for the industrial-scale manufacture of the titled compound.
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