Copper-Catalyzed C(sp3)-H Functionalization of Ketones with Vinyl Azides: Synthesis of Substituted-1H-pyrroles.
2016
Copper-catalyzed C(sp3)–H functionalization of ketones with vinyl azides for the synthesis of substituted pyrroles has been developed. The method is a straightforward and efficient way to access a series of 2,3,5-trisubstituted-1H-pyrroles in modest to excellent yields with broad functional group tolerance under mild conditions.
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