Are weak blood groups important to look for in kidney transplantation? A case report on interchanging blood groups

The principles of ABO compatibility are fundamental to clinical solid organ transplantation, and conventional blood grouping techniques may mislabel patients with rare blood groups. We present a case of a kidney donor and her recipient who were mislabeled by conventional blood grouping methodology due to the presence of weak blood groups in both individuals, which were identified on detailed analysis, thus avoiding the need to undergo unnecessary desensitization protocols. The recipient underwent a successful transplant with the same donor and continues to do well 6 months after the transplant.