신이식환자에서 Cyclosporine 의 치험 ; 제 1 보

Between May, 1984 and May, 1985, twenty-one patients received kidney transplants from living related donor in 18 and from non-related donor in 3 were treated with cyclosporin A(CsA). On May, 1985, actuarial patient survival rates at one year were 94% in the CsA group and 80g in the Aza group(p<0.05), and the corresponding graft survival rates were 94%< in the CsA group and 76% in the Aza group(p＜ 0.01). The hirsutium, hypertension, tremor, nephrotoxicity k infection were common side effect in CsA group. The nephrotoxicity, however, was easily manageable through management strategy. Episodes of acute rejection were not frequent & occurred 2 times in 2 patients. All the patients except one had good renal funcuion immediately after transplantation, In one case treated with CsA-steroid, a fatal complication occurred due to status epilepticus with acute brain dysfunction. Results of these experience have shown that CsA was superior immunosuppresive regimen used. With small dose of steroid.