소변시료에서 메트암페타민 및 대마성분 검출에 대한 면역시험법 비교 평가

In this study, we used immunoassay for the preliminary test to detect methamphetamine, cannabinoids and their metabolites in human urine. Specifically, we compared four different immunoassays: FPIA (Fluorescent Polarization ImmunoAssay), EMIT (Enzyme-Multiplied Immunoassay Technique), CEDIA (Cloned Enzyme Donor ImmunoAssay) and KIMS (Kinetic Interaction of Microparticles in Solution). We evaluated the performance of immunoassays using common parameters: true positive, true negative, false positive and false negative. Sensitivity, specificity, accuracy and false positive/negative rates were also calculated. The findings from this study indicated that FPIA, EMIT, CEDIA and KIMS can provide acceptable preliminary results to detect methamphetamine, cannabinoids and their metabolites in forensic toxicology.