A New and Simple Synthetic Route to Furaniod Linalool Oxide from Citral

Linalool oxide is an aroma material found naturally in apple, bitter orange peel oil, raspberry, beer, brandy, tea, pear, brandy, and other plants. A variety of production of linalool oxide has been reported. We report a new method for the chemical synthesis of furanoid linalool oxide from 3,7-dimethyl-2,6-octadienal in this paper. A short and efficient synthesis of furaniod linalool oxide was accomplished in five steps from 3,7-dimethyl-2,6-octadienal which was underwent epoxidation, acid rearrangement, NaBH4 reduction, the selectively protection of resulting hydroxyl, and the elimination reaction. The GC content was 98%. The over yield was 52.84%. All of the intermediates and products were characterised by IR, NMR and MS.