Outcomes of pancreaticoduodenectomy for pancreatic malignancy in octogenarians: an American College of Surgeons National Surgical Quality Improvement Program analysis.

Abstract Background Most series analyzing outcomes of pancreaticoduodenectomy in octogenarians are limited by a small sample size. The investigators used the American College of Surgeons National Surgical Quality Improvement Program database for an analysis of the impact of advanced age on outcomes after pancreatic cancer surgery. Methods The National Surgical Quality Improvement Program database from 2005 to 2010 was accessed to study the outcomes of 475 pancreaticoduodenectomies performed in patients ≥80 years of age compared with 4,102 patients t tests. A multivariate logistic regression was used to analyze factors associated with 30-day mortality and the occurrence of major complications. Results Octogenarians had significantly more preoperative comorbidities compared with patients Conclusions Although octogenarians have an increased risk for mortality and major complications compared with patients