An alternative the Nigerian pharmaceutical composition and preparation method Shah

2012 
The present invention relates to a pharmaceutical composition of dasatinib and its preparation method. The composition comprising an effective amount of a pharmaceutically acceptable excipient and dasatinib, dasatinib is anhydrous, pharmaceutically acceptable excipients contained in the weight percentage of 3% to 15% of the retarder; the blocker is hydrophilic gel material is selected from hydroxypropylmethyl cellulose, methyl cellulose, carbopol, or alginate. The present invention also provides a pharmaceutical composition dasatinib preparation. Dasa present invention is a pharmaceutical composition imatinib-blockers can improve the microenvironment of solid preparations, on the one hand to improve the stability of the formulation, on the other hand can control the dissolution rate of oral formulations. Simple preparation process of the present invention, low-cost, non-polluting.
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