Molecular Dynamics, Biological Study and Extractive Spectrophotometric Determination of Vanadium (V) - 2-methyl-8-quinolinol Complex

An extractive spectrophotometric method is developed for the trace determination of vanadium(V). 2-Methyl-8-quinolinol(MQ) reacts with vanadium(V) to form a 1:2 (V : MQ) light brown complex in aqueous medium at 0.05 M CH3COOH concentration which is quantitatively extractable into chloroform exhibiting maximum absorbance in the range 397- 405 nm..The complex is synthesized in 1:2 ratio and the structure of the formed complex is elucidated on the basis of IR, NMR and TGA techniques aided with computational studies. The formed V(V)-MQ complex is also screened for its in vitro antimicrobial activity.The method obeys Beer’s law upto 6.2 µg V ml-1 with molar absorptivity and Sandell’s sensitivity of 2.449 × 103 L mol-1 cm-1 and 0.0208 µg V cm-2 , respectively, at 400 nm.The method is simple, rapid and has good reproducibility with a standard deviation of ± 0.0027 absorbance units .