Spinal location of lymphoma tumor as an uncommon first manifestation of AIDS; A case report

Abstract: Introduction: Patients struggling with acquired immune deficiency syndrome (AIDS) are significantly at higher risk of developing lymphoma . Lymphoma usually occurs in uncommon extra-nodal sites in immune deficient patients. In current study we have aimed to introduce a case with spinal Burkitt's lymphoma (BL) as the first manifestation of HIV. Case presentation: A 36-year-old drug addicted, married male was free of drug abuse since 10 years ago, referred to Al-Zahra Hospital with complaint of back pain that radiated to lower limb. Intervertebral disk protrusion at L5-S1 level and paravertebral abscess at T10-T11 levels were found in MRI. Due to history of IV-drug using, HIV tests were sent for him and viral load was 52107 copies/ml and genotype indicated infection of HIV-1. Number of CD-4+ cells was checked as well. The number equaled 24. After necessary consultants, he underwent decompressive laminectomy and fixation and sample biopsy in order of infection/neoplasm ruling-out was sent. Results of biopsy showed histological and immunohistochemical findings in favor of burkiit's lymphoma. Conclusion: BL can be the first manifestation of HIV that uncommon site of it can act as a clue to early diagnosis of HIV/AIDS. Key words: AIDS, HIV, Lymphoma, Burkitt's lymphoma, back pain