The contribution of magnetic resonance imaging in the differential diagnosis of optic nerve damage

In this paper we review the findings of magnetic resonance imaging (MRI) in optic neuritis and visual dysfunction due to other optic neuropathies. With advances in MRI technology, it has become possible to visualise optic nerve pathology. STIR and RARE sequences, contrast-enhanced sequences, and phased array surface coils are technical developments that provide fine anatomical detail and that are sensitive to pathological changes. MRI can offer information in the differential diagnosis of optic neuropathies, the monitoring of their treatment, and in some instances should provide new insights into the underlying pathophysiological mechanisms.