Highly Selective Intramolecular Addition of C—N and S—N Bonds to Alkynes Catalyzed by Palladium: A Practical Access to Two Distinct Functional Indoles.

Palladium-catalyzed highly selective intramolecular addition of C–N and S–N bonds to alkynes has been achieved, and two distinct functional indoles were synthesized rapidly from the same set of substrates in a catalyst-controlled manner. This protocol features high atom economy, moderate to high yields and excellent selectivity, thus affording a practical approach to functional indoles.