OXIDATION-REDUCTION INDICATOR PATTERNS IN REGENERATION OF THE FORELEG AND TAIL OF TRITURUS TOROSUS LARVAE

1. Amputation of foreleg and tail at various levels is followed almost immediately by increased intracellular indophenol reaction and oxidation of dyes in reduced solution.2. In the leg the injury reaction and the later regenerative outgrowth show the anteroposterior and dorsiventral patterns of the leg.3. Development of the first three toes at almost the same time in the course of regeneration of the foot, rather than in the sequence characteristic of the development of the intact leg probably results from the increased metabolism in the regenerating, as compared with the intact leg.4. In tail regeneration the injury reaction is more rapid and extends much farther anterior to the surface of amputation in the caudal axial region than in dorsal and ventral fins. Also the later regenerative outgrowth is much more rapid in and near the caudal axial region than in the fins. The reactivity gradient decreases anteriorly.5. The increase in reactivity anterior to the level of tail amputation is present not only d...