Fungal Cerebral Embolic Infarction by Rhino-Orbitocranial Aspergillosis

Aspergillosis of paranasal sinuses is a rare infection with invasion of surrounding soft tissues, orbit and anterior cranial base. Eighteen years old immunocompetent man presented with gross facial swelling, proptosis and unilateral blindness. Histopathology was reported as invasive aspergillosis. The patient was given systemic antifungal therapy in the form of liposomal amphotericin B. He died of cerebral infarction by fungal embolism. Aspergillus fumigatus was the causative organism.