The Synthesis of Uracils as Anticonvulsants

Abstract A convenient laboratory synthesis has been devised by which a series of new 5‐alkyluracils has been prepared for evaluation as anti‐convulsants. Certain other 5‐substituted uracils and their N,N‐dimethyl derivatives, and related compounds, have also been synthesized. The anticonvulsant activity of uracil and thymine has been surpassed by several members of this new series.