[The mutagenic action of the DNA fragments of bovine adenovirus type 3 (BAV-3) containing early E1 (oncogene) and E4 regions].

: A study of mutagenic action of DNA fragments of bovine adenovirus type 3 (BAV-3), containing early E1 (oncogenic) and E4 regions has been carried out. Viral DNA was digested with Xba 1 restriction endonuclease. The mutagenic effect revealed itself by induction of resistance to 6-mercaptopurine in Chinese hamster cells. The data obtained suggest that the early regions E1 and E4 can cause mutagenic effect in mammalian cells.