Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses

Yiliang Chen,Moua Yang,Wenxin Huang,Wenjing Chen,Yiqiong Zhao,Marie L. Schulte,Peter J Volberding,Zachary J. Gerbec,Michael T. Zimmermann,Atefeh Zeighami,Wendy Demos,Jue Zhang,Darcy A. Knaack,Brian C. Smith,Weiguo Cui,Subramaniam Malarkannan,Komal Sodhi,Joseph I. Shapiro,Zijian Xie,Daisy Sahoo,Roy L. Silverstein

Mitochondrial Metabolic Reprogramming by CD36 Signaling Drives Macrophage Inflammatory Responses

2019

Rationale: A hallmark of chronic inflammatory disorders is persistence of pro-inflammatory macrophages in diseased tissues. In atherosclerosis this is associated with dyslipidemia and oxidative str...

Keywords:

Reprogramming
Cardiology
Diabetes mellitus
Biology
Internal medicine
Dyslipidemia
CD36
Oxidative phosphorylation
Immunology
Proinflammatory cytokine
metabolic reprogramming
Mitochondrion

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