A kind of high-dissolution fenofibrate and preparation method thereof

2017 
The invention discloses a kind of high-dissolution fenofibrate and preparation method thereof, the high-dissolution fenofibrate is included using sulfobutyl ether beta cyclodextrin to fenofibrate raw material, it is then spray-dried after be made again with auxiliary material mixing direct tablet compressing.Preparation method of the present invention solves conventional method and the problem of drug quality causes low dissolution rate, poor bioavailability is difficult to control in production;Relatively existing direct tablet compressing and wet granulation technology, effectively increase the solubility of medicine so that the dissolution rate of medicine is better, improves bioavilability.
    • Correction
    • Source
    • Cite
    • Save
    • Machine Reading By IdeaReader
    0
    References
    0
    Citations
    NaN
    KQI
    []