An Efficient and Scalable Ritter Reaction for the Synthesis of t‐Butyl Amides
2014
A scalable procedure for the conversion of nitriles to N-tert-butyl amides via the Ritter reaction was optimized employing tert-butyl acetate and acetic acid. The reaction has a broad scope for aromatic, alkyl, and α,β-unsaturated nitriles.
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