Sustained release liquid medicine

PURPOSE: To obtain a stable sustained release liquid medicine excellent in stability of coating film for applying a complex of a medicine-resin, causing no breakage of the coating film even during long-term storage and capable of retaining release control property of the medicine over a long period. CONSTITUTION: The objective sustained release liquid medicine contains 0.1-45.0 (w/v)% diffusion barrier film coating material obtained by absorbing a pharmacologically active medicine into an ion exchange resin to afford a complex of medicine-resin, treating the complex with a solvation agent (e.g. polyethylene glycol) and coating the treated complex with ethyl cellulose having 44.0-47.5% ethoxy group content and (A) 0.05-0.15% methyl para-oxybenzoate, 0.05-0.075% ethyl para-oxybenzoate, 0.03-0.05% propyl para-oxybenzoate or 0.01-0.015% butyl para-oxybenzoate, (B) 0.01-0.02% methyl para-oxybenzoate and 0.01-0.02% propyl para-oxybenzoate or (C) 0.1-0.5% sodium benzoate as preservatives. COPYRIGHT: (C)1993,JPO&Japio