Unusual case of proximal calciphylaxis without renal failure.

Background:Calciphylaxis is a rare syndrome of vascular calcification with subsequent cutaneous and tissue necrosis. It usually manifests as a complication of end-stage renal failure, affecting 1 to 4% of long-term dialysis patients. Very exceptionally, it can occur without chronic renal failure.Objective:The goal of this study was to discuss an exceptional case of extensive calciphylaxis in the absence of chronic renal failure and its successful management.Methods:We present a case of a 31-year-old woman with extensive proximal, ulcerated calciphylaxis without associated chronic renal failure. Our patient had quite a few risk factors associated with the pathogenesis of calciphylaxis, such as obesity, malnutrition, and a transient episode of acute renal failure.Results:She was successfully treated with sodium thiosulfate, extensive wound debridement (more than 30% total body surface), and subsequent skin grafts. The patient has miraculously survived this often fatal condition.Conclusion:Calciphylaxis can ...