Collagen-Based Fillers as Alternatives to Cyanoacrylate Glue for the Sealing of Large Corneal Perforations

Purpose:To describe the use of collagen-based alternatives to cyanoacrylate glue for the sealing of acute corneal perforations.Methods:A collagen analog comprising a collagen-like peptide conjugated to polyethylene glycol (CLP-PEG) and its chemical crosslinker were tested for biocompatibility. These