Comparison of 7 T and 3 T MRI in patients with moyamoya disease

Abstract Magnetic resonance imaging and magnetic resonance angiography (MRI/MRA) are widely used for evaluating the moyamoya disease (MMD). This study compared the diagnostic accuracy of 7 Tesla (T) and 3 T MRI/MRA in MMD. In this case control study, 12 patients [median age: 34 years; range (10–66 years)] with MMD and 12 healthy controls [median age: 25 years; range (22–59 years)] underwent both 7 T and 3 T MRI/MRA. To evaluate the accuracy of MRI/MRA in MMD, five criteria were compared between imaging systems of 7 T and 3 T: Suzuki grading system, internal carotid artery (ICA) diameter, ivy sign, flow void of the basal ganglia on T2-weighted images, and high signal intensity areas of the basal ganglia on time-of-flight (TOF) source images. No difference was observed between 7 T and 3 T MRI/MRA in Suzuki stage, ICA diameter, and ivy sign score; while, 7 T MRI/MRA showed a higher detection rate in the flow void on T2-weighted images and TOF source images (p