A Case of Pediatric Thrombotic Microangiopathy in a Jehovah’s Witness

Thrombotic microangiopathy (TMA) is a disease affecting vessel walls leading to aggregation of platelets and wall thickening. Laboratory findings include hemolytic anemia, thrombocytopenia, and elevated LDH. TMA is a rare finding in the pediatric population. The main causes are thrombotic thrombocytopenic purpura (TTP), toxin-mediated hemolytic uremic syndrome (D+ HUS), and atypical HUS. Less commonly TMA can occur as result of malignant hypertension (MHTN), lupus/antiphospholipid syndrome, or medications. We present a 15 year-old previously healthy Jehovah’s witness on no medications who presented in hypertensive emergency, found to have …