Generalized primary amyloidosis: Report of a case with amyloid verrucous valvular lesions and nephrotic syndrome

Abstract 1. 1. A case of generalized primary amyloidosis with congestive heart failure and nephrotic syndrome is reported. Extensive deposits of amyloid were seen in several viscera, including the heart and kidneys. The heart revealed verrucous valvular lesions, and the kidney showed diffuse glomerular involvement. 2. 2. The various types of amyloidosis are discussed, with particular reference to the distribution of the deposits in the heart and kidneys. 3. 3. It is emphasized that amyloidosis should always be considered in the differential diagnosis in cases of cardiac failure and nephrotic syndrome.