Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques

Taylor W. Foreman,Allison N. Bucsan,Smriti Mehra,Charles A. Peloquin,Lara A. Doyle,Kasi E. Russell-Lodrigue,Neel R. Gandhi,John D. Altman,Cheryl L. Day,Joel D. Ernst,Henry M. Blumberg,Jyothi Rengarajan,Deepak Kaushal

Isoniazid and Rifapentine Treatment Eradicates Persistent Mycobacterium tuberculosis in Macaques

2019

Taylor W. Foreman
Allison N. Bucsan
Smriti Mehra
Charles A. Peloquin
Lara A. Doyle
Kasi E. Russell-Lodrigue
Neel R. Gandhi
John D. Altman
Cheryl L. Day
Joel D. Ernst
Henry M. Blumberg
Jyothi Rengarajan
Deepak Kaushal

Rationale: Direct evidence for persistence of Mycobacterium tuberculosis (Mtb) during asymptomatic latent TB infection (LTBI) in humans is currently lacking. Moreover, while a 12-week regimen of on...

Keywords:

Diabetes mellitus
Anesthesia
Regimen
Mycobacterium tuberculosis
Rifapentine
Granuloma
Isoniazid
Immunology
Medicine
Lung
Asymptomatic
Latent tuberculosis

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