Effect of hypotonic liquid containing colloid on hemorrhagic dogs with celiac seawater immersion wound

Objective: To determine hypotonic liquid containing colloid on hemorrhagic dogs with celiac seawater immersion wound. Methods: Thirty-five dogs were randomly divided into five groups: control group(group A), 0.9%NaCl therapy group(group B) and 0.45%NaCl therapy group (group C), 5% glucose therapy group(group D) and hypotonic liquid containing colloid therapy group(group E). Changes of mean artery pressure(MAP), cardiac output(CO), urine volume, plasma osmotic pressure and pathologic changes of lung and brain were observed. Results: hypotonic liquid containing colloid could effectively ameliorate MAP and CO, improve urine volume, decrease plasma osmotic pressure and prevent occurrence of lung and brain edema. Conclusion: Hypotonic liquid containing colloid can exert satisfactory therapeutic effects on hemorrhagic dogs with celiac seawater immersion wound.