Computational Modeling of Blast Induced Human Injury Biomechanics and Traumatic Brain Injury

The work aims to understand the blast induced injury mechanism and facilitate the development of protection and treatment. Novel multi-scale and multi-physics computational models of coupled blast physics, whole body biodynamics and injury biomechanics are presented. Modeling components include blast wave threat characterization, anatomy-based high-fidelity human model, human body blast loading, biodynamics and body/brain biomechanics leading to primary injury, as well as the multi-physics solver suitable for high-performance computing. The coupled gas dynamics and biomechanics solutions were validated against shock tube test data. The parametric simulations of human body exposed to blasts were conducted to find biomechanical responses and brain injury mechanism.