Multivesicular bodies in cortical dendrites of two patients with Alzheimer's disease.
1978
Abstract Biopsy fragments from the frontal cortex of 2 patients with Alzheimer's disease were studied with ultrastructural and cytochemical methods. A great number of light and dark, acid phosphatase positive, multivesicular bodies were observed in dendrites and their spines, in all cortical layers, being more abundant in layers 3 and 4. A close topographic relationship between these organelles and post-synaptic membranes was found. It is postulated that these findings might be related to the neurite formation of the senile plaques and to the synaptic involvement in Alzheimer's disease.
Keywords:
- Correction
- Source
- Cite
- Save
- Machine Reading By IdeaReader
17
References
14
Citations
NaN
KQI