Multidimensional spatial characterization of the tumor microenvironment (TME) in synchronous melanoma metastases (SMM) to yield insights into mixed responses to therapy in metastatic melanoma (MM) patients (pts).

Alexandre Reuben,Michael T. Tetzlaff,Christine N. Spencer,Giang Ong,Kristi Barker,Peter A. Prieto,Christopher P. Vellano,Jinho Lee,Courtney W. Hudgens,Meredith Ann McKean,Vancheswaran Gopalakrishnan,Robert Sloane,Sangeetha Reddy,Chris Merritt,Sarah Warren,Joseph Beechem,Michael A. Davies,Patrick Hwu,Gordon B. Mills,Jennifer A. Wargo

Multidimensional spatial characterization of the tumor microenvironment (TME) in synchronous melanoma metastases (SMM) to yield insights into mixed responses to therapy in metastatic melanoma (MM) patients (pts).

2017

9575Background: Although both targeted and immune therapies have significantly improved outcomes for mm pts, only a minority of pts experience durable responses with many pts with multiple SMM demo...

Keywords:

Melanoma
Pathology
Cancer research
Tumor microenvironment
Medicine
metastatic melanoma
Oncology
Internal medicine
immune therapy

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