Improved Fmoc-Solid Phase Synthesis of β-Amyloid Peptides Using DBU as Nα-Deprotection Reagent

Alzeheimer’s Disease (AD) is the most common form of dementia affecting society today. It is a neurodegenerative disease, the histopathological features of which include extracellular deposition of amyloid β peptide (Aβ)-loaded senile plaques in the brain parenchyma and blood vessels.