Considerations for Nonmelanoma Skin Cancer: Clinical Presentation

Lymphadenopathy of the groin, or inguinal lymphadenopathy, may be a feature of a number of systemic diseases, both benign and malignant. Benign causes of inguinal lymphadenopathy include infection, as well as vascular and autoimmune disease. Malignant groin lymphadenopathy may derive from primary skin tumors (melanoma, squamous cell carcinoma, and Merkel cell carcinoma being the most common) of the lower extremity or lower trunk, perineum, reproductive tracts, and lower gastrointestinal tract and leukemias and lymphomas [1]. This chapter focuses on inguinal lymph node metastasis from non-melanoma cutaneous malignancies.