Platelets amplify endotheliopathy in COVID-19

Tessa J. Barrett,MacIntosh Cornwell,Khrystyna Myndzar,Christina C. Rolling,Yuhe Xia,Kamelia Drenkova,Antoine Biebuyck,Alexander T. Fields,Michael Tawil,Elliot Luttrell-Williams,Eugene Yuriditsky,Grace Smith,Paolo Cotzia,Matthew D. Neal,Lucy Z. Kornblith,Stefania Pittaluga,Amy Rapkiewicz,Hannah M. Burgess,Ian Mohr,Kenneth A. Stapleford,Deepak Voora,Kelly V. Ruggles,Judith S. Hochman,Jeffrey S. Berger

Platelets amplify endotheliopathy in COVID-19

2021

Given the evidence for a hyperactive platelet phenotype in COVID-19, we investigated effector cell properties of COVID-19 platelets on endothelial cells (ECs). Integration of EC and platelet RNA se...

Keywords:

Platelet
Effector cell
severe acute respiratory syndrome coronavirus 2
Phenotype
Virology
Coronavirus disease 2019
2019 20 coronavirus outbreak
RNA
Biology

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