Straightforward synthesis and antioxidant studies of chalcogenoaziridines

Abstract Herein we reported the synthesis of chalcogenoaziridines through the introduction of the organoselenium moiety in the aziridine framework through the nucleophilic substitution of the OTs leaving group. In addition, the antioxidant activity, as reflected by free radical scavenging, was also evaluated. The new seleno aziridine 6a showed more effective antioxidant compared to other compounds. These findings also suggest that seleno aziridine 6a is a promising antioxidant and that its activity is not influenced by the presence of the substituents attached into the aromatic ring.