Value of CT guided ^125I seeds implantation for vertebra metastasis

Objective To evaluate the clinical value of ^125I seeds implantation for vertebra metastasis. Methods By CT guide, ^125I seeds were implanted in 22 vertebra metastasis of 15 patients. 3-6 months later, pain and metastasis biggest diameter were observed to judge therapeutic effect. Results In 22 spinal and paraspinal metastases after implantation of particles, complete remission of pain （0 grade） 14, partial remission （ Ⅰ grade） 6, a slight relief （ Ⅱ grade） 2, the total effective rate was 90.9% （u=5.41, P〈0.001）. Change of spinal and paraspinal metastases size： 4 complete remission, 12 partial response, 6 stable disease, local control rate was 72.7%. Conclusion CT guided ^125I seed implantation in vertebra metastasis is safe, minimally invasive, and possesses a high efficacy. Key words: Spinal neoplasms;  Neoplasms metastasis;  Iodine radioisotopes;  Brachytherapy