The Effect of Clozapine Treatment of Refractory Schizophrenia

Objective Discuss the effect of clozapine treatment of refractory schizophrenia. Methods Select 88 cases of patients with treatment- resistant schizophrenia,randomly divided into experimental group and control group,each group of 44 cases,control group risperidone was given to the experimental group on the basis of risperidone therapy using clozapine treatment,to observe the therapeutic effect of two groups of patients. Results Experimental treatment in patients with total effective rate 93. 2%,control group total effective rate was 79. 5%; The experimental group after treatment in patients with PANSS score significantly lower than the control group,compared to significant difference( P 0. 05),with statistical significance. Conclusion For treatment- resistant schizophrenia patients,the use of clozapine treatment,can effectively improve the treatment effect,reduce the patient's clinical symptoms,improve quality of life,is worth promoting.