Synthesis, Spectral, and Antimicrobial Activity of 6-Alkylcarbamato-2,10-dichloro-12- trichloromethyl-12 H -dibenzo[d,g][1,3,2]- dioxaphosphocin 6-Oxides

Abstract 6-Alkylcarbamato/alkylthiocarbamato-2,10-dichloro-12-trichloromethyl-12H-dibenzo[d,g][1,3,2]-dioxaphosphocin 6-oxides (4a–f) have been synthesized by the condensation of 2,2-bis-(2-hydroxy-5-chlorophenyl)-1,1,1-trichloroethane (3) with dichlorophosphinyl carbamates (2a–f) of different alcohols/thiols in the presence of triethylamine in dry toluene. The title compounds structures were confirmed by different spectral (elemental, IR and 1H, 13C & 31P NMR) studies and found to possess antimicrobial activity.