2-β-(N-arylpiperazino) ethyl indandiones-1,3 and indandiols-1,3

By the action of N-arylpiperazines on the tosylates of 2-β-hydroxyethyl-2-phenyl and 2-methylsubstituted indandiones-1,3 one obtains 2-β-(N-arylpiperazino) ethyl derivatives of 2-substituted indandiones-1,3 which are reduced by sodium borane to the corresponding indandiol-1,3 derivatives. The arylpiperazino derivatives of 2-substituted indandiones-1,3 and indandiols-1,3 have neurotropic properties. A certain association between structure, toxicity, and pharmacological action of these compounds was noted.