Descifrando la patogenia de la COVID-19

COVID-19 is an acute respiratory disease, caused by a new SARS-CoV-2 coronavirus On March 11, 2020, the WHO declared COVID-19 a pandemic The speed with which the COVID-19 pandemic has been addressed has been possible thanks to the production of scientific knowledge with the immediate publication, and results in real-time and communicating through social networks The pathophysiology of COVID-19 is complex and is currently not fully understood In this sense, in the present study, we analyze different aspects related to the entry of SARS-Cov-2 into the human host cell through the binding to its receptor, the angiotensin-converting enzyme 2 (ACE2), the exacerbated inflammatory response or cytokine storm, and factors that contribute to a greater contagion by infected people called super-transmitters Topics that are essential to understand and deal with COVID-19 © 2020 Academia Nacional de Medicina All rights reserved