THE INTERRELATION BETWEEN THE SYSTEMIC INFLAMMATORY RESPONSE AND TYPE OF NUTRITION SUPPORT CURRENT OF SYSTEM INFLAMMATORY RESPONSE IN CHILDREN WITH EARLY ADHESIVE OBSTRUCTION UNDERGOING SURGERY

The aim of the study was to estimate the interrelation between the type of nutrition support with the course of system inflammatory response in children with acute appendicular peritonitis and early adhesive ileus obstruction undergoing videoendosurgery. It was a prospective, controlled, nonrandomized unicentral study. 92 patients were included in the study. The endpoints were as follows: dynamics of clinical signs of SIRS, level of C-reactive protein, levels of pro-inflammatory cytokines (tumor necrosis factor and interleykin-6), procalcitonin (PCT) level. 49 patients (main group) received the combination of early parenteral nutrition (Nutriflex from the first postoperative day) with enteral tube feeding from the second postoperative day and sipping from the 3-4 th days. 43 patients (control group) received the full parenteral nutrition (Nutriflex) from the second postoperative day with transition to sipping nutrition from the 4 th postoperative day. The postoperative period was accompanied by a comparable growth of levels of CRP and pro-inflammatory cytokines. the accelerated recovery of nutrition status, normalization of procalcitoninum level in the blood serum, and reducted duration of SIRS was noticed in the children from the main group.