Merrifield, Alpha-MethoxyPhenyl (MAMP) resin; a new versatile solid support for the synthesis of secondary amides

Abstract The synthesis and initial reactivity of a new resin, termed MAMP (Merrifield, Alpha-Methoxy Phenyl), which is useful for the on-resin synthesis and mild acidolytic cleavage of compounds containing secondary amide functionality, is reported. Synthesis of a model peptoid utilising MAMP-resin is described.