Inhaled colistin for the treatment of ventilator-associated tracheobronchitis in critically ill patients

Limited evidence exists regarding the efficacy of inhaled antibiotics in ventilator-associated tracheobronchitis (VAT) [1,2]. The aim of this study was to assess the effect of monotherapy with nebulized colistin on clinical and microbiological outcomes in critically ill patients with VAT due to polymyxin-only susceptible Gram-negative bacteria.