Safety and activity of venetoclax in combination with high-dose cytarabine in children with relapsed or refractory acute myeloid leukemia.

Seth E. Karol,Thomas B. Alexander,Soumyasri Das Gupta,Stanley Pounds,Kristin Canavera,Jeffery M. Klco,Norman J. Lacayo,Ching-Hon Pui,Joseph T. Opferman,Jeffrey E. Rubnitz

Safety and activity of venetoclax in combination with high-dose cytarabine in children with relapsed or refractory acute myeloid leukemia.

2019

Seth E. Karol
Thomas B. Alexander
Soumyasri Das Gupta
Stanley Pounds
Kristin Canavera
Jeffery M. Klco
Norman J. Lacayo
Ching-Hon Pui
Joseph T. Opferman
Jeffrey E. Rubnitz

10004Background: Venetoclax is an orally available BCL-2 antagonist with demonstrated activity in adults with newly diagnosed or relapsed acute myeloid leukemia (AML). Here, we describe the first u...

Keywords:

Refractory
Oncology
Cytarabine
Pathology
Myeloid leukemia
Medicine
Internal medicine
Venetoclax
newly diagnosed
high dose cytarabine
Antagonist

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